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Pharmaceutical firms have had a complicated history of distributing patented medication in the developing world. But, as with many infectious disease drugs, the vast majority of people that needed it lived in the developing world and couldn't afford it. Almost 37 million individuals are contaminated with river blindness, of which approximately 300,000 have been blinded or visually impaired. The variety of cases indicating the presence of an epidemic varies in line with the agent, the scale of the outbreak, and the kind of inhabitants exposed. He emphasized that this disaster is unprecedented and that preparation for an epidemic does not point out readiness for a pandemic. He recommended that the private sector handle security issues around the drug provide and related collateral injury outcomes as the pandemic worsens. Severity assessment of a pandemic is based on mode of transmission as well as agent pathogenicity and virulence. With the continued use of Mectizan®, it's hoped that transmission of river blindness can be interrupted and the disease will probably be just about eliminated. Since 1993, Lions Clubs International Foundation has awarded US$33 million to help the distribution of river blindness medication, Mectizan®, to roughly 251 million individuals in 15 African and Latin American countries.

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